Pigmented villonodular synovitis (PVS) A case report.

Pigmented villonodular synovitis (PVNS) is benign proliferative disorder of the synovium of unknown origin. PVNS is divided into intra-articular and extra-articular form which may present as i) diffuse or ii) localised/nodular form. It is commonly seen in knee joint but hip, ankle, shoulder, wrist & other joints can be involved. It is usually seen in young adults from 20-50 years of age. It is seen more in men than women. A 26 years old female presented to our OPD with chief complaints of pain & swelling over right knee since 1 year. MRI right knee was suggestive of synovial thickening & collection in anterior aspect of knee with peripheral hemosiderin deposits which is suggestive of PVNS. Arthroscopic resection of this lesion was performed & histological report was revealed presence of giant cells & hemosiderin laden macrophages which are suggestive of PVNS. The case is presented because of unusual involvement in a female. Milwaukee Shoulder Syndrome (MSS) may be associated with PVNS.